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Hussain Lab is a “Translation Nanotoxicology and Environmental Health Laboratory”. We study pulmonary and systemic health impacts of inhalation exposures/co-exposures to environmentally relevant particulates (Particulate Matter, Engineered Nanomaterials) and gases (O3, NOx etc.,). Areas of interest currently under investigation are:

1) Inflammation, injury and repair of lungs in response to environmental insults

2) Lung and gut microbial dysbiosis after environmental exposures

3) Gene x Environment interaction in environmental lung injury

4) Systemic outcomes after gestational inhalation exposures

We utilize state of the art Pulmonary Function Measurements, Air-Liquid Interface Cultures, 3-D Organoids and disease animal models (genetic and acquired susceptibility) to elaborate organismal/cellular responses and mechanistic pathways after environmental exposures.