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Peer-Reviewed Scientific Publications

Total Citations >7097 H-index- 21, i10-index 25 (UPDATED April, 2020)

  1. Hussain S, Johnson CG, Sciurba J, Cyphert JM, Stober VP, Rice AB, Bulek K, Liu C, Aloor J, Gowdy K, Foster WM, Hollingsworth JW, Fessler MB, Li X, Tighe RM, Garantziotis S. 2019 TLR5 participates in TLR4 signaling and biases towards MyD88 activation in environmental lung injury. Elife. 2020 Jan 28;9. pii: e50458
  2. Whitehead GS, Hussain S, Fannin R, Innes CL, Schurman SH, Cook DN, Garantziotis S. 2019 TLR5 activation through flagellin promotes airway inflammation in asthma. Lung. 2020 Apr;198(2):289-298
  3. Hussain S. Measurement of Nanoparticle-Induced Mitochondrial Membrane Potential Alterations. Methods Mol Biol. 2019;1894:123-131
  4. Mohammadinejad R, Moosavi MA, Tavakol S, Vardard DO, Hosseini V, Rahmati M, Dinig M, Hussain S, Mandegary A, Klionskyj D. Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles Autophagy. 2019 15:4-33.
  5. Snyder R, Hussain S, Randell SH, Tucker CJ and Garantziotis S. Impaired ciliogenesis in differentiating human bronchial epithelia exposed to multi-walled carbon nanotubes. Part Fibre Toxicol. 2017, 13; 14(1):44.
  6. Hilton MG, Taylor AJ, Hussain S, Dandley EC, Griffith EH, Garantziotis S, Parson GN, Bonner JC and Bereman MS. Mapping Differential Cellular Protein Response of Mouse Alveolar Epithelial Cells to Multi-Walled Carbon Nanotubes as a Function of Atomic Layer Deposition Coating. Nanotoxicology 2017 11(3):313-326
  7. Hussain S, Ji Z, Taylor AJ, Miller-DeGraff L, George M, Tucker J, Chang CH, Li R, Bonner JC, Garantziotis S. Multiwalled Carbon Nanotube Functionalization with High Molecular Weight Hyaluronan Significantly Reduces Pulmonary Injury. ACS Nano 2016. 10(8):7675-88.
  8. Hussain S, Kodavanti PP, Marshburn JD, Janoshazi A, Marinakos SM, George M, Rice A, Wiesner MR and Garantziotis S. Decreased Uptake and Enhanced Mitochondrial Protection Underlie Reduced Toxicity of Nanoceria in Human Macrophages Compared to Monocytes. 2016. J. Biomed. Nanotechnol. 2016. 12, 2139–2150
  9. Kolinsky DJ,..,Hussain S,.., Zughaier SM, Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Autophagy 2016;12(1):1-222.
  10. Guadagnini R, Moreau K, Hussain S, Marano F, Boland S. Interaction of nanoparticles used in medical applications with lung epithelial cells: cytotoxicity, oxidative stress and inflammatory response. Nanotoxicology 2015, 9 S1:25-32
  11. Hussain S, Sangtian S, Anderson SM, Snyder RJ, Marshburn JD, Rice AB, Bonner J, Garantziotis S. Inflammasome Activation in Airway Epithelial Cells after Multi-Walled Carbon Nanotube Exposure Mediates a Profibrotic Response in Lung Fibroblasts. Part Fibre Toxicol. 2014, 11:28.
  12. Hussain S, Garantziotis S, Rodrigues-Lima F, Dupret JM, Baeza-Squiban A, Boland S. Intracellular signal modulation by nanomaterials. Adv Exp Med Biol. 2014, 811:111-34.
  13. Snyder R, Hussain S, Rice A, Garantziotis S. Multi-Walled Carbon Nanotubes Induce Altered Morphology and Loss of Barrier Function in Human Bronchial Epithelia at Non-Cytotoxic Doses. Int. J. Nanomedicine 2014, 9:4093-105
  14. Boland S, Hussain S, Baeza-Squiban A, “Carbon Black and Titanium Dioxide Nanoparticles Induce Distinct Molecular Mechanisms of Toxicity” Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014, 6(6):641-52
  15. Yokel RA, Hussain S, Garantziotis S, Demokritou P, Castranova V and Cassee F. The Yin: An adverse health perspective of nanoceria: uptake, distribution, accumulation, and the mechanisms of its toxicity. Environ. Sci.: Nano 2014, 1(5):406-428.
  16. Taylor AJ, McClure C, Shipley-Philips JK, Thompson EA, Hussain S, Garantziotis S, Parsons GN, Bonner JC. Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In vitro and Reduces Lung Fibrosis in Mice In vivo PLOS One 9(9):e106870
  17. Hussain S and Garantziotis S. Interplay between apoptotic and autophagy pathways after exposure to cerium dioxide nanoparticles in human monocytes. Autophagy. 2013. 9(1):101-103.
  18. Hussain S, Vanoirbeek J, Boland S, Haenen S, Marano F, Nemery B, Hoet PHM. Local lung inflammation leads to targeting of distinct organs by gold nanoparticles. BioMed Res Int (formerly Journal of Biomedicine and Biotechnology) 2013:923475
  19. Hussain S, Al-Nsour F, Rice A, Marshburn J, Ji Z, Zink I, Walker N, Garantziotis S. Cerium dioxide nanoparticles induce cell death in human peripheral blood monocytes through apoptosis and autophagy. ACS Nano. 2012. 6(7):5820-5829.
  20. Hussain S, Vanoirbeek J, Boland S, Marano F, Nemery B, Hoet PHM. Nanoparticles modulate in vivo chemical sensitization. Part Fibre Toxicol. 2012. 9:15.
  21. Hussain S, Al-Nsour F, Rice AB, Marshburn J, Ji Z, Zink JI, Yingling B, Walker NJ, Garantziotis S. Cerium dioxide nanoparticles do not modulate the lipopolysaccharide-induced inflammatory response of human monocytes. Int. J. Nanomedicine 2012. 2; 7:1387-97
  22. Hussain S, Vanoirbeek J, Hoet P. Interactions of nanomaterials with the immune system. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012. 4(2):169-83.
  23. Hussain S, Jeroen JAJ, Luyts K, De Vooght V, Verbeken E, Boland S, Marano F, Nemery B, Hoet PHM. Lung exposure to nanoparticles modulates an asthmatic response in a mouse model of asthma. Eur Respir J. 2011. 37(2):299-309.
  24. Sanfins E, Dairou J, Hussain S, Busi F, Chaffotte A, Rodrigues-Lima F and Dupret JM. Carbon black nanoparticles impair acetylation of aromatic amine carcinogens through inactivation of arylamine N-acetyltransferase enzymes ACS Nano. 2011. 5(6) :4504-4511
  25. Marano F, Hussain S, Rodrigues-Lima F, Baeza-Squiban A and Boland S. Nanoparticles: molecular targets and cell signaling. Arch Toxicol 2011. 85:733–741.
  26. Boland S, Guadagnini R, Baeza-Squiban A, Hussain S, Marano F. Nanoparticles used in medical applications for the lung: hopes for nanomedicine and fears for nanotoxicity. J. Phys.: Conf. Ser. 2011. 304: 012031
  27. Hussain S, Thomson CJL, Ferecatu I, Borot C, Andreau K, Martens JA, Fleury J, Baeza-Squiban A, Marano F and Boland S. Carbon Black and Titanium Dioxide Nanoparticles Elicit Distinct Apoptotic Pathways in Bronchial Epithelial Cells. Part Fibre Toxicol. 2010. 7:10
  28. Val S, Hussain S*, Boland S, Hamel R, Baeza-Squiban A, Marano F. Carbon black and titanium dioxide nanoparticles induce pro-inflammatory responses in bronchial epithelial cells: need for multiparametric evaluation due to adsorption artifacts. Inhal Toxicol. 2009. 21: Sl 1:115-22. *Equal contribution first authors
  29. Hussain S, Boland S, Baeza-Squiban A, Hamel R, Thomassen LCJ, Martens JA, Billon-Galland MA, Fleury-Feith J, Moisan F, Pairon JC, Marano F. Oxidative stress and proinflammatory effects of carbon black and titanium dioxide nanoparticles: Role of particle surface area and internalized amount. Toxicology 2009. 260, 142–149.
  30. Hussain S, Khan MZ, Khan A, Javed I, Asi MR. Toxico-pathological effects in rats induced by concurrent exposure to aflatoxin and cypermethrin. Toxicon 2009. 53, 33–41.
  31. Hussain S, I. Ali, A. Khan. Hematological and Plasma Proteins Findings in Fayoumi Hen Suffering from ascites. Pak Vet. J. 2004. 24(4), 203-204.


  • Hussain S. Measurement of Nanoparticle Induced Mitochondrial membrane potential Alterations in Methods in Molecular Biology Series Nanotoxicity: Methods and Protocols Eds: Qunwei Zhang in Press 2018
  • Hussain S, Garantziotis S, et al. 2014 Intracellular signal modulation by nanomaterials. In Nanomaterial: Impacts on Cell Biology and Medicine. Eds: David Capco and Yongsheng Chen. Springer USA.
  • Baeza-Squiban A., Boland S., Hussain S., and Marano F. 2010 Health Effects of Nanoparticles. In Systems Toxicology: from omics technology to nanotechnology. Eds: Saura C. Sahu and Daniel A. Casciano. John Wiley and Sons Ltd. ISBN: 978-0-470-68401-6